Conventional treatments for substance abuse can have limited success for some and be ineffective for others. In an attempt to expand the available treatment options, researchers are developing vaccines for addiction. Orson et al. review the current status of vaccines to treat nicotine, cocaine, phenylcyclidine (PCP), methamphetamine, heroin, and morphine for which conventional inpatient and outpatient treatment programs have shown limited success(Orson et al., 2008). In this review, we discuss only the status of vaccines currently undergoing clinical trials with humans. Methods The authors provide a critical review of current clinical vaccines and animal studies that focus on reactions to... Read more →