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Wednesday, April 21, 2010


The largest trial of electronic cigarettes so far, of 40 participants and conducted in New Zealand in 2009, shows that the nicotine e-cigarette significantly reduces cravings.
Bullen et al, Tobacco Control journal, published 9 April 2010. Full text at www.healthnz.co.nz/News2010.htm

As in the Eissenberg trial above, we reported low nicotine delivery in comparison with own brand cigarettes on a puff by puff basis. However, no-one has so far formally characterised how committed vapers use e-cigarettes. Many appear to puff very frequently, (feasible, as no lighting up involved). Two puffs every 5 minutes equals 24 puffs per hour, as against 7-20 puffs for a tobacco cigarette.

Also both trials refer to first generation e-cigarettes. In the last year vapers have been busy modifying these cigarettes (www.vapersclub.com) to deliver a noticeable nicotine kick, and factories in China can rapidly manufacture to new designs. Further research is needed to keep up with developments.

The e-cigarette with its visible “smoke” may raise smokers’ expectations – a partial placebo effect. The New Zealand study (blinded for strength) found a strong placebo effect in the first 15 minutes, before this was overtaken by the full strength e-cigarette effect. The full strength e-cigarettes was preferred to the medicinal nicotine inhaler, as more pleasant to use, the vapor being less harsh.

I welcome contacts from others interested in researching e-cigarettes further.

Murray Laugesen e-cigarette researcher www.healthnz.co.nz
(no financial interest in nicotine or tobacco companies).

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